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Latest research publications and updates from the Institute

Mitochondrial ROS Research Featured Publication

Mitochondrial Reactive Oxygen Species: A Unifying Mechanism in Long COVID and Spike Protein-Associated Injury

Halma MTJ, Tuszynski JA, Marik PE et al.

Our latest collaborative publication in Biomolecules presents groundbreaking findings linking mitochondrial reactive oxygen species (ROS) to the pathophysiology observed in Long COVID and spike protein-associated conditions. This work provides a mechanistic framework for understanding post-viral metabolic dysfunction and points toward therapeutic interventions.

METABOLISM POST-VIRAL
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2025 Publications

Publication

Breaking the Silence: Recognizing Post-Vaccination Syndrome

Halma MTJ, Tuszynski JA, Marik PE et al.

Heliyon — 6 citations. A comprehensive review on the recognition and characterization of post-vaccination syndrome, providing clinical guidance and research directions.

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Publication

Metabolic Modulation as a Therapeutic Strategy for PACVS

Halma MTJ, Tuszynski JA, Marik PE et al.

Biomedicine & Pharmacotherapy — Review of therapeutic approaches targeting metabolic dysfunction in post-acute COVID vaccine syndrome patients.

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Publication

Restoring Trust in Vaccination

Halma MTJ, Tuszynski JA, Marik PE et al.

Frontiers in Medicine — Listening to patients and acknowledging Post-Acute COVID Vaccine Syndrome to improve public health outcomes.

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Publication

Potent Broad-Spectrum Anti-Coronaviral Frameshift Inhibitors

Neupane K, Sekar G, Omar SI, Tuszynski JA et al.

bioRxiv — Virtual screening identifies potent frameshift inhibitors effective against multiple coronavirus strains through RNA binding mechanisms.

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Publication

Blood Biomarkers for All-Cause Mortality Risk

Halma MTJ, Aniwar A, Tuszynski JA, Varon J, Marik PE

Archives of Gerontology and Geriatrics Plus — Accessibility and clinical utility of blood biomarkers for lifestyle medicine interventions.

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Publication

Recent Update on siRNA Therapeutics

Ebenezer O, Tuszynski JA, Wong GJ et al.

International Journal of Molecular Sciences — 28 citations. Comprehensive review of siRNA therapeutic development and delivery strategies.

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2026 Publications

Clinical Trial

Metabolic Modulation for Post-Vaccination Syndrome: Clinical Trial Protocol

Halma MTJ, Tuszynski JA, Marik PE et al.

Study protocol for a prospective randomized controlled trial evaluating the effectiveness of metabolic modulation therapies in treating post-vaccination syndrome.

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Publication

Acute Management of Measles: A Systematic Review

Halma MTJ, Tuszynski JA, Marik PE et al.

Antiviral Research — Comprehensive systematic review of therapeutic strategies for acute measles management.

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